Neuronale Dynamik über die Lebensspanne
Lifespan Neural Dynamics Group
Diese ehemalige Emmy Noether-Gruppe (2017–2023) wurde von Douglas Garrett geleitet und war Teil des Max Planck UCL Centre for Computational Psychiatry and Ageing Research am Berliner Standort.
© Mehau Kulyk / Science Photo Library / Universal Images Group
Das Forschungsinteresse der Lifespan Neural Dynamics Group (LNDG) richtet sich darauf, wie und warum das menschliche Gehirn so von Moment zu Moment fluktuiert. Insbesondere untersuchen wir Hirnsignalvariabilität und -dynamik in Bezug auf sechs zentrale Forschungsthemen:
- Entwicklung über die Lebensspanne
- Kognition
- Strukturelle/Funktionelle Vernetzung
- Neuromodulation
- Transkranielle Stimulation
- Methoden
Förderung
- Forschungsbereich Entwicklungspsychologie, Max-Planck-Institut für Bildungsforschung, Berlin
- Max Planck UCL Centre for Computational Psychiatry and Ageing Research
- Emmy Noether-Programm der Deutschen Forschungsgemeinschaft (DFG) von 2017 bis 2023
Ausgewählte Publikationen
, , & (2025). Healthy aging delays and dedifferentiates high-level visual representations. Current Biology, 35(9), 2112–2127.e6. https://doi.org/10.1016/j.cub.2025.03.062
, , & (2025). Modulation of brain signal variability in visual cortex reflects aging, GABA, and behavior. eLife, 13, Article e83865. https://doi.org/10.7554/eLife.83865
, , , , , , & (2025). Single-neuron spiking variability in hippocampus dynamically tracks sensory content during memory formation in humans. Nature Communications, 16, Article 236. https://doi.org/10.1038/s41467-024-55406-4
, , , , , , , , , , , , , & (2025). Toward a functional future for the cognitive neuroscience of human aging. Neuron, 113(1), 154–183. https://doi.org/10.1016/j.neuron.2024.12.008
, , , & (2024). Broadscale dampening of uncertainty adjustment in the aging brain. Nature Communications, 15, Article 10717. https://doi.org/10.1038/s41467-024-55416-2
, , , & (2023). The impact of the human thalamus on brain-wide information processing. Nature Reviews Neuroscience, 24, 416–430. https://doi.org/10.1038/s41583-023-00701-0
, , , , , & (2022). Moment-to-moment brain signal variability reliably predicts psychiatric treatment outcome. Biological Psychiatry, 91(7), 658–666. https://doi.org/10.1016/j.biopsych.2021.09.026
, , , , , , & (2021). Lost dynamics and the dynamics of loss: Longitudinal compression of brain signal variability is coupled with declines in functional integration and cognitive performance. Cerebral Cortex, 31(11), 5239–5252. https://doi.org/10.1093/cercor/bhab154
, , & (2021). Thalamocortical excitability modulation guides human perception under uncertainty. Nature Communications, 12, Article 2430. https://doi.org/10.1038/s41467-021-22511-7
, , , & (2021). Behavior needs neural variability. Neuron, 109(5), 751–766. https://doi.org/10.1016/j.neuron.2021.01.023
, , , , & (2020). Boosts in brain signal variability track liberal shifts in decision bias. eLife, (9), Article e54201. https://doi.org/10.7554/eLife.54201

