Lifespan Rhythms of Memory and Cognition (RHYME)
The overarching objective of this project is to understand how the dynamic interplay of maturation, personal experiences, and senescence drives and affects plastic changes on neural and behavioral levels across the lifespan. To this end, the RHYME project combines experimental approaches and longitudinal study designs with multi-modal data sources from several neuroimaging methods to uncover the foundations of intra- and inter-individual variations in intellectual functions such as perception, attention, learning, and memory.
Currently, the following themes build the focus of the project’s research activities:
- How do lifespan changes in neuroanatomy and neurochemistry during maturation and senescence affect mechanisms of rhythmic neural activity that support attention, learning, and (working) memory?
- What are the mechanisms driving the surprisingly close co-development of sleep physiology and improved cognition during childhood, as well as its decline during aging?
- Do qualitative transitions in memory development during childhood depend on the maturation of intra-hippocampal structures?
- Is it possible to derive personalized descriptions of maturational/senescent timing and intellectual potential within a given individual?
We often carry out electroencephalography (EEG), during which the electrical currents in the brain are registered on the scalp via electrodes. In some studies, we also use magnetic resonance imaging (MRI), where the structure and functioning of the brain is made visible by magnetic fields.