Kristine Walhovd,University of Oslo - Timing of influences on brain and cognition across the lifespan

LIP Distinguished Lecture

Kristine Walhovd

Following persons over time in is key to understand the development of brain and cognitive differences across the lifespan, when and how they can be affected. Searching for factors that modify outcomes, we need to distinguish how such factors associate with differences in level (intercept) of brain and cognition to begin with, versus slope of change. In this talk, I stress the need to account for early life factors to better understand and target modifiable factors in adulthood and aging. There is evidence to indicate that individual differences, in the level of brain and cognition, many of which present early in life, may appear more stable, larger, and more pervasive than differences in change across the lifespan. Investigating how potentially modifiable factors associate with both level and change in brain and cognition may reduce the risk of ascribing undue importance to factors operating in older age. In this talk I discuss both observational and experimental data to illuminate factors that may influence brain and cognition, and their potential timing, in a lifespan perspective.

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