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Ludmila Müller

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Research Coordinator
+49 30 82406-380
lmueller [at] mpib-berlin [dot] mpg [dot] de
221

Short CV: 

Dr. rer. nat., 1997, Eberhard-Karls-Universität Tübingen
Dipl. Biologin, 1994, Eberhard-Karls-Universität Tübingen
Dipl. Biologin, 1986, Ural-State-University, Sverdlovsk


Research Interests: 
  • Neuroimmunosenescence
  • Neuroinflammation and brain plasticity in aging
  • Immunosenescence
  • Interdisciplinary gerontology
  • Tumour immunology
     

Selected Literature: 

Müller, L., Hamprecht, K., & Pawelec, G. (2017). The role of CMV in "immunosenescence". In V. Bueno, J. M. Lord, & T. A. Jackson (Eds.), The ageing immune system and health (pp. 53-68). Cham: Springer. doi:10.1007/978-3-319-43365-3_4
Full text

Di Benedetto, S., Müller, L., Wenger, E., Düzel, S., & Pawelec, G. (2017). Contribution of neuroinflammation and immunity to brain aging and the mitigating effects of physical and cognitive interventions. Neuroscience & Biobehavioral Reviews. 75, 114-128. doi:10.1016/j.neubiorev.2017.01.044
Full text

Müller, L., & Pawelec, G. (2016). The aging immune system: Dysregulation, compensatory mechanisms, and prospects for intervention. In M. R. Kaeberlein & G. M. Martin (Eds.), The handbook of the biology of aging (8th ed., pp. 407-431). London: Academic Press.

Müller, L., & Pawelec, G. (2015). As we age: Does slippage of quality control in the immune system lead to collateral damage? Ageing Research Reviews, 23(Part A), 116-123. doi:10.1016/j.arr.2015.01.005
Full text

Di Benedetto, S., Derhovanessian, E., Steinhagen-Thiessen, E., Goldeck, D., Müller, L., & Pawelec, G. (2015). Impact of age, sex and CMV-infection on peripheral T cell phenotypes: Results from the Berlin BASE-II Study. Biogerontology. doi:10.1007/s10522-015-9563-2
Full text

Pawelec, G., & Müller, L. (2015). The immune system. In J. Vijg, J. Campisi, & G. J. Lithgow (Eds.), Molecular and cellular biology of aging (pp. 300-324). Washington, DC: The Gerontological Society of America.
Full text

Müller, L., & Pawelec, G. (2014). Aging and immunity: Impact of behavioral intervention. Brain, Behavior, and Immunity. doi:10.1016/j.bbi.2013.11.015
Full text

Müller, L., & Pawelec, G. (2014). Immune escape and aging of the immune system compromises the immune response to tumor antigens. In R. Rees (Ed.), Cancer immunology and immunotherapy. Oxford: Oxford University Press.

Pawelec, G., & Müller, L. (2014). Immune compromise in the elderly. In K. E. Sullivan & E. R. Stiehm (Eds.), Stiehm's immune deficiencies (pp. 811-815). Amsterdam: Elsevier. doi:10.1016/B978-0-12-405546-9.00042-X
Full text

Müller, L., Fülöp, T., & Pawelec, G. (2013). Immunosenescence in vertebrates and invertebrates. Immunity and Ageing, 10:12. doi:10.1186/1742-4933-10-12
Full text

Müller, L., Pawelec, G., & Derhovanessian, E. (2013). The immune system during aging. In P. Calder & P. Yagoob (Eds.), Diet, immunity and inflammation (pp. 631-651). Cambridge, UK: Woodhead Publishing.

Müller, L., & Pawelec, G. (2013). Introduction to ageing of the adaptive immune system. In J. A. Bosch, A. C. Phillips, & J. M. Lord (Eds.), Immunosenescence: Psychological and behavioural determinants (pp. 17-33). New York: Springer.

Pawelec, G., Müller, L., Fülöp, T., Dunn-Walters, D. (in press). Immune System Changes and Immunosenescence. Oxford Textbook of Geriatric Medicine, Oxford University Press, 3rd Edition.

open all Curriculum Vitae

zuklappen Publications

Pawelec, G., Müller, L., Fülöp, T., & Dunn-Walters, D. (in press). Immune system changes and immunosenescence (3rd ed.). In J.-P. Michel, L. Beattie, F. Martin, & J. Walston (Eds.), Oxford textbook of geriatric medicine. Oxford: Oxford University Press.

Di Benedetto, S., Müller, L., Wenger, E., Düzel, S., & Pawelec, G. (2017). Contribution of neuroinflammation and immunity to brain aging and the mitigating effects of physical and cognitive interventions. Neuroscience & Biobehavioral Reviews, 75, 114-128. doi:10.1016/j.neubiorev.2017.01.044
Full text

Müller, L., Hamprecht, K., & Pawelec, G. (2017). The role of CMV in "immunosenescence". In V. Bueno, J. M. Lord, & T. A. Jackson (Eds.), The ageing immune system and health (pp. 53-68). Cham: Springer. doi:10.1007/978-3-319-43365-3_4
Full text

Müller, L., & Pawelec, G. (2016). The aging immune system: Dysregulation, compensatory mechanisms, and prospects for intervention. In M. R. Kaeberlein & G. M. Martin (Eds.), The handbook of the biology of aging (8th ed., pp. 407-431). London: Academic Press.

Di Benedetto, S., Derhovanessian, E., Steinhagen-Thiessen, E., Goldeck, D., Müller, L., & Pawelec, G. (2015). Impact of age, sex and CMV-infection on peripheral T cell phenotypes: Results from the Berlin BASE-II Study. Biogerontology, 16, 631-645. doi:10.1007/s10522-015-9563-2
Full text

Müller, L., & Pawelec, G. (2015). As we age: Does slippage of quality control in the immune system lead to collateral damage? Ageing Research Reviews, 23(Part A), 116-123. doi:10.1016/j.arr.2015.01.005
Full text

Pawelec, G., & Müller, L. (2015). The immune system. In J. Vijg, J. Campisi, & G. J. Lithgow (Eds.), Molecular and cellular biology of aging (pp. 300-324). Washington, DC: The Gerontological Society of America.
Full text

Müller, L., & Pawelec, G. (2014). Aging and immunity: Impact of behavioral intervention. Brain, Behavior, and Immunity, 39, 8-22. doi:10.1016/j.bbi.2013.11.015
Full text

Müller, L., & Pawelec, G. (2014). Immune escape and aging of the immune system compromises the immune response to tumor antigens. In R. C. Rees (Ed.), Tumor immunology and immunotherapy (pp. 415-432). Oxford: Oxford University Press.

Pawelec, G., & Müller, L. (2014). Immune compromise in the elderly. In K. E. Sullivan & E. R. Stiehm (Eds.), Stiehm's immune deficiencies (pp. 811-815). Amsterdam: Elsevier. doi:10.1016/B978-0-12-405546-9.00042-X
Full text

Müller, L., Fülöp, T., & Pawelec, G. (2013). Immunosenescence in vertebrates and invertebrates. Immunity & Ageing, 10:12. doi:10.1186/1742-4933-10-12
Full text

Müller, L., & Pawelec, G. (2013). Introduction to ageing of the adaptive immune system. In J. A. Bosch, A. C. Phillips, & J. M. Lord (Eds.), Immunosenescence: Psychological and behavioral determinants (pp. 17-33). New York: Springer.

Müller, L., Pawelec, G., & Derhovanessian, E. (2013). The immune system during aging. In P. Calder & P. Yaqoob (Ed.), Diet, immunity and inflammation (pp. 631-651). Oxford: Woodhead Publishing.

Knights A. J., Weinzierl A. O., Flad ,T., Guinn B. A., Mueller L., Mufti G. J., Stevanovic S., Pawelec G. (2006). A novel MHC-associated proteinase 3 peptide isolated from primary chronic myeloid leukaemia cells further supports the significance of this antigen for the immunotherapy of myeloid leukaemias. Leukemia. 20(6):1067-72

Flad, T., Müller, L., Tolson, J., Dihazi, H., Grigorova, V., Bogumil, R., Beck, A., Thedieck, C., Klatt, T., Pawelec, G., Kalbacher, H., Mueller, C.A. (2006). T-cell epitope definition by differential mass spectrometry: identification of a novel, immunogenic HLA-B8 ligand directly from renal cancer tissue. Proteomics. 6(1):364-74.

Müller, L., McArdle, S., Derhovanessian, E., Flad, T., Knights, A., Rees, R., & Pawelec, G. (2005) Book Chapter „ Current strategies for discovery of tumor antigens”. The Humana Press Inc., New Jersey.

Müller, L., & Pawelec, G. (2005) Chapter: Chronic Myelogenous Leukemia in book "Progress in Leukemia Research” by Nova Science Publishers. New York.

Müller, L, & Pawelec G. (2003).Cytokines and antitumor immunity. Technol.Cancer Res.Treat. 2:183-194.

Müller, L., Knights, A., & Pawelec, G. (2003). Synthetic peptides derived from the Wilms' tumor 1 protein sensitize human T lymphocytes to recognize chronic myelogenous leukemia cells. Hematol.J. 4:57-66.

Müller, L., Kiessling, R., Rees, R. C., & Pawelec, G. (2002). Escape mechanisms in tumor immunity: an update. J.Environ.Pathol.Toxicol.Oncol. 21:277-330.

Müller, L., & Pawelec, G. (2002). Immunogenicity of WT1 peptides as potential target antigens in CML. Leuk Lymphoma 43(9).

Müller, L., & Pawelec, G. (2002). Chronic phase CML patients possess T cells capable of recognising autologous tumour cells. Leuk. Lymphoma 43: 943-951.

Knights, A. Zaniou, J., A., Rees, R. C., Pawelec, G., & Müller, L. (2002). Prediction of an HLA-DR-binding peptide derived from Wilms' tumour 1 protein and demonstration of in vitro immunogenicity of WT1(124-138)- pulsed dendritic cells generated according to an optimised protocol. Cancer Immunol. Immunother. 51: 271-281.

Müller, L., Provenzani, C., & Pawelec ,G. (2001). Generation of chronic myelogenous leukemia-specific T cells in cytokine- modified autologous mixed lymphocyte/tumor cell cultures. J. Immunother. 24: 482-492.

Müller, L., Provenzani, C., Faul,C., & Pawelec, G. (2001). Recognition of chronic myelogenous leukaemia cells by autologous T lymphocytes primed in vitro against the patient's dendritic cells. Br. J. Haematol. 112: 740-748.

Pawelec, G., Müller, L., & Wagner, W. (2001). MHC class II-restricted tumor antigens and CD4+ T cells play a role in hematological malignancies as well as solid tumors. Trends Immunol. 22: 422-423.

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