EnglishDeutsch

Sofja Kovalevskaja Research Group

Sofja Kovalevskaja Research Group on Plasticity of Brain and Behavior in Adulthood and Old Age

This Research Group was led by Martin Lövdén and dealt with the following topics: Aging-related reductions in abilities, such as working memory, reasoning, episodic memory, and spatial orientation, begin roughly around the age of 65, but different individuals perform at different levels and change at different rates. Epidemiological work suggests that individuals with a lifestyle rich in mental, physical, and social stimulation experience less cognitive decline in old age. However, we know little about the mechanisms through which experience modulates cognitive aging. For example, we do not know whether the favorable infl uences of an enriched lifestyle on cognitive change come from direct effects of mental stimulation on cognitive performance or through indirect routes, such as avoidance of negative effects on cognition (e. g., depression, stress, or vascular conditions). The goal of the Sofja Kovalevskaja Research Group on the Plasticity of Brain and Behavior in Adulthood and Old Age was to fill this research lacuna. The studies conducted as a part of the Research Group are briefly described below.

Sofja Kovalevskaja

Sofja Kovalevskaja

Sofja Kovalevskaja was born in Moscow on January 15, 1850 and died on January 29, 1891 in Stockholm. Sie was a major Russian mathematician who earned her doctorate in 1874 at the University of Göttingen. In 1889 she was the first woman to be appointed to a full professorship in Northern Europe. The prize named after her is financed by the German Federal Ministry of Education and Research and awarded to young scientists every two years by the Alexander von Humboldt Foundation.

SPACE

This study was carried out by the Sofja Kovalevskaja Research Group within the framework of the Sensorimotor-Cognitive Couplings project. The study investigated the practice-related changes of spatial navigation performance and underlying brain structures in younger and older adults.

Researchers: Martin Lövdén, Nils Bodammer, Ulman Lindenberger, Sabine Schaefer

Predoctoral Research Fellow: Hannes Noack

Collaborators: Lars Bäckman (Karolinska Institute, Stockholm), Emrah Düzel (University College London & Universität Magdeburg), Simone Kühn (Ghent University)

COGITO

In collaboration with the Intra-Person Dynamics project, this study investigates the plasticity of intelligence and underlying brain structures in younger and older adults. One hundred younger and 100 older adults performed perceptual speed, episodic memory, and working-memory tasks for 100 daily sessions. Subsamples underwent MRI, DTI, fMRI, and EEG before and after training.

Researchers: Florian Schmiedek, Martin Lövdén, Annette Brose, Nils Bodammer, Ulman Lindenberger

Former Predoctoral Research Fellow: Julia K. Wolff (meanwhile at German Centre of Gerontology)

Collaborators:  Emrah Düzel (University College London & Universität Magdeburg), Simone Kühn (Ghent University), Naftali Raz (Wayne State University)

Swedish Military School of Interpreters

Conscript interpreters in the Swedish military learn a new language from scratch to native-like proficiency within a year. Our studies of these conscripts investigated behavioral and brain changes induced by language acquisition. A new series of studies are being conducted in collaboration with the ConMem project.

Researchers: Martin Lövdén, Nils Bodammer

Predoctoral Research Fellow: Johan Mårtensson (Lund University)

Collaborators: Mikael Johansson (Lund University), Magnus Lindgren (Lund University), Lars Nyberg (Umeå University)

Background

In 2006 Martin Lövdén received the Alexander von Humboldt Foundation's Sofja Kovalevskaja Prize. Financed by the German Federal Ministry for Education and Research, the one million Euro Award enables young scientists from outside Germany to finance their own research groups at a German university or other research institution of their choice. The funding period of the Award extended over 4 years (2007–2010).

New Project

References

Lövdén, M., Bäckman, L., Lindenberger, U., Schaefer, S., & Schmiedek, F. (2010). A theoretical framework for the study of adult cognitive plasticity. Psychological Bulletin, 136, 659–676. doi: 10.1037/ a0020080

Lövdén, M., Bodammer, N. C., Kühn, S., Kaufmann, J., Schütze, H., Tempelmann, C., et al. (2010). Experience-dependent plasticity of white-matter microstructure extends into old age. Neuropsychologia, 48, 3878–3883. doi: 10.1016/j.neuropsychologia. 2010.08.026

Lövdén, M., Ghisletta, P., & Lindenberger, U. (2005). Social participation attenuates decline in perceptual speed in old and very old age. Psychology and Aging, 20, 423–434. doi: 10.1037/0882-7974.20.3.423

Lövdén, M., Schaefer, S., Noack, H., Kanowski, M., & Kaufmann, J. (2011). Performance-related increases in hippocampal N-acetylaspartate (NAA) induced by spatial navigation training are restricted to BDNF Val homozygotes. Cerebral Cortex, 21, 1435–1442. doi: 10.1093/cercor/bhq230

Mårtensson, J. & Lövdén, M. (2011). Do intensive studies of a foreign language improve associative memory performance? Frontiers in Psychology, 2: 12. doi: 10.3389/fpsyg.2011.00012
Full text